LYMPHOID NEOPLASIA Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia

1Division of Pediatric Hematology-Oncology and 2Department of Pediatrics, University of California, San Francisco, San Francisco, CA; 3Department of Pathology, Johns Hopkins University, Baltimore, MD; 4Department of Laboratory Medicine, University of Washington, Seattle, WA; 5Department of Pathology and University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM; 6Departments of Pathology and Pediatrics, The Ohio State University, Nationwide Children’s Hospital, Columbus, OH; 7Department of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplantation, Children’s Hospital Colorado and The University of Colorado School of Medicine, Aurora, CO; and 8Department of Pathology, St Jude Children’s Research Hospital, Memphis, TN